Alfaxan® Multidose
28 day shelf-life after broaching

Alfaxan Multidões

Alfaxan Multidose is the new preserved formulation of alfaxalone combining the reliability you have come to expect from Alfaxan with the versatility that comes with an extended shelf life of 28 days following vial broach.

  • Preserved formulation reduces risk of microbial contamination
  • and provides repeatable and reliable anaesthesia from the same vial for up to 28 days.

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Active Constituents

  • Alfaxalone 10 mg/mL

Indications

Induction and maintenance of anaesthesia in dogs and cats.

Induction of anaesthesia in pet rabbits.

Dosage

Dose recommendations for induction of anaesthesia

  Dogs Cats Rabbits
Recommended Dose 1-9
  Un-premedicated Premedicated Un-premedicated Premedicated Premedicated
mg/kg 3 2 5 5 0.4
ml/kg 0.3 0.2 0.5 0.5 0.2

 

Dose recommendations for maintenance of anaesthesia

  Dogs   Cats  
  Un-premedicated Premedicated Un-premedicated Premedicated
Dose for constant rate infusion
mg/kg/hour 8 - 9 6 - 7 10 - 11 7 - 8
mg/kg/minute 0.13 0 0.15 0.10 - 0.12 0.16 - 0.18 0.11 - 0.13
mL/kg/minute 0.013 - 0.015 0.010 - 0.012 0.016 - 0.018 0.011 - 0.013
Bolus dose for each 10 minutes maintenance
mg/kg 1.3 - 1.5 1.0 - 1.2 1.6 - 1.8 1.1 - 1.3
mL/kg 0.13 - 0.15 0.10 - 0.12 0.16 - 0.18 0.11 - 0.13

 

  1. Engbers S., Larkin A., Rousset N., Melanie Prebble M., Jonnalagadda M., Knight K.G. & Pang D.S.J. (2017). Comparison of a Supraglottic Airway Device (V-gel®) with Blind Orotracheal Intubation in Rabbits. Front Vet Sci 4: 49
  2. Fisher P & Graham J (2018). Chapter 10: Rabbits. In: Exotic Animal Formulary: 5th edition. Carpenter J.W. (ed). Elsevier, St. Louis, Missouri
  3. Gil A.G., Silván G., Villa A. & Illera J.C. (2012). Heart and respiratory rates and adrenal response to propofol or alfaxalone in rabbits. Vet Rec 170: 444
  4. Gomes F.E, de Matos R. & Ledbetter E. (2018). Phacoemulsification of bilateral cataracts in two pet rabbits. Open Vet J 8(2): 125-130
  5. Grint N.J., Smith H.E. & Senior J.M. (2009). Clinical evaluation of alfaxalone in cyclodextrin for the induction of anaesthesia in rabbits. Vet Rec 163: 395-396
  6. Hedley J., Stapleton N., Muir C., Priestnall S. & Smith K. (2019). Cutaneous botryomycosis in two pet rabbits. J Exot Pet Med 28: 143-14
  7. Meredith A (ed) (2015). BSAVA Small Animal Formulary, 9th edition – Part B: Exotic Pets. British Small Animal Veterinary Association, Gloucester, UK
  8. Swisher S., Lennox A. & Blair L. (2018). Successful removal of a tracheal foreign body secondary to nasograstric tube placement in a rabbit (Oryctolagus cuniculus). J Exot Pet Med 27: 32–35
  9. Tutunari A.C., Sonea A., Drion P., Serteyn D. & Sandersen C. (2013). Anaesthetic induction with alfaxalone may produce hypoxemia in rabbits premedicated with fentanyl/droperidol. Assoc Vet Anaesth & American College of Vet Anesth Analg 40: 650–659