Methadyne

Methadyne

Methadyne is used in practice for Analgesia for moderate or severe pain or as part of a patient’s premedication for general anaesthesia or to provide neuroleptanalgesia.

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Active Constituents

Methadone 10mg/ml

Indications

Methadyne can be used in dogs and cats for:

  • Analgesia for moderate or severe pain.
  • As part of a patient’s premedication for general anaesthesia or to provide neuroleptanalgesia.

Effects

  • Approximate time to peak effect:
    • 15 minutes when administered IM1
    • Within 10 minutes when administered IV1
  • Approximate duration of action is often reported as 3-4 hours with a range of 1.5 to 6.5 hours as per the drug datasheet1

References:

  1. Dugdale A (2010). Veterinary Anaesthesia.  Principles to Practice. Wiley-Blackwell.

Dosage

Species Dose Route
Dog 0.5 to 1 mg/kg 
(0.05 to 0.1 ml/kg) SC, IM or IV
Cat 0.3 to 0.6 mg/kg (0.03 to 0.06 ml/kg) IM

The individual response to methadone is varied, and depends partly on the dose administered, the age of the patient, level of current pain, pain sensitivity and general condition of the patient. Therefore, the optimal dose should be based on the practitioner’s judgement of each individual patient.
Methodyne can be antagonised with naloxone. Naloxone should be given to effect and a starting dose of 0.1mg/kg IV is recommended.